The Collection

Three formulations.
One protocol.

Each RevelleCare product will be compounded to pharmaceutical standards by a licensed Canadian pharmacy and dispensed under physician supervision. No two women's menopause is identical — our planned protocol will adapt to yours. Products are not yet available — launching Fall 2026.

RevelleCare Estrogen Repair Cream
Prescription Required

Formulation 01

Estrogen
Repair Cream

Estradiol 0.01% Collagen synthesis · Epidermal thickness
Estriol 0.3% Barrier repair · Elasticity · ERβ activation

The cornerstone of the RevelleCare protocol. Formulated with two complementary estrogens that act on distinct receptor pathways — estradiol (ERα) drives collagen and elastin production, while estriol (ERβ) repairs the barrier and improves skin flexibility.

Clinical data shows up to +75% increase in epidermal thickness, +38% increase in collagen density, and 61–100% wrinkle reduction with this active combination. Formulated for daily morning use.

Clinically Demonstrated Outcomes

  • +75% epidermal thickness (Moraes et al., 2009)
  • +38% dermal collagen density (Fuchs et al., 2003)
  • 61–100% wrinkle reduction (Schmidt et al., 1996)
  • Improved skin hydration and elasticity
  • Restoration of barrier function
RevelleCare Night Renewal Cream
Prescription Required

Formulation 02

Night
Renewal Cream

Tretinoin 0.05% Cell renewal · Collagen stimulation · MMP inhibition
Estriol 0.03% Barrier support · Retinoid tolerance · ERβ protection

Designed for overnight regeneration. Tretinoin, the gold-standard retinoid, accelerates cellular turnover and inhibits collagen-degrading enzymes — while estriol at a protective low dose maintains barrier integrity and reduces the irritation often associated with retinoid therapy.

The night cycle aligns with your skin's natural circadian repair biology, maximizing tretinoin's mechanism of action. The result: visible improvement in texture, fine lines, and firmness with reduced sensitivity.

Clinical Benefits

  • Accelerated epidermal cell turnover
  • MMP-1 inhibition — reduced collagen breakdown
  • New collagen deposition via RAR + ER dual pathways
  • Reduced retinoid-associated irritation (estriol buffer)
  • Improved fine lines, texture, and pigmentation at 12 weeks
RevelleCare Non-Hormonal Repair Cream
No Prescription Required

Formulation 03

Non-Hormonal
Repair Cream

Niacinamide (B3) Active Barrier · Brightening · Anti-inflammatory
Vitamin C Active Antioxidant · Collagen cofactor · Brightening
Vitamin E Active Lipid antioxidant · Photoprotection · Barrier
Bioactive Peptides Active Collagen signalling · Firming · Renewal

A sophisticated non-prescription companion for women who prefer hormone-free support — or as an adjunct to the RevelleCare Rx protocol. Combines four synergistic antioxidant and signalling actives proven in independent clinical trials.

Bioactive matrikine peptides signal fibroblasts to produce new collagen, while the vitamin complex addresses oxidative stress, barrier disruption, and uneven tone — three of the most visible consequences of menopausal skin aging.

Demonstrated Benefits

  • Up to 44% reduction in wrinkle depth (peptides, 12 wks)
  • Improved skin barrier — reduced TEWL
  • Reduction in hyperpigmentation (niacinamide)
  • Antioxidant protection against environmental stressors
  • Suitable for hormonal contraindications or preference

The RevelleCare Protocol

Physician-guided layering of active ingredients for maximum efficacy — morning and evening, synchronized with your skin's natural biology.

AM

Morning Ritual

1
Gentle Cleanser

pH-balanced, non-stripping formula to preserve morning barrier integrity

2
Estrogen Repair Cream

Apply as directed by your physician. Let absorb fully before SPF.

Rx
3
SPF 30+ Broad Spectrum

Essential protection — estrogen therapy increases UV sensitivity

PM

Evening Ritual

1
Double Cleanse

Remove SPF and environmental residue before actives application

2
Night Renewal Cream

Tretinoin + Estriol — apply to dry skin 20 minutes post-cleanse

Rx
3
Occlusive Moisturizer

Optional: seal tretinoin for enhanced absorption (sandwich method)

Physician-personalized dosing

All application frequencies, concentrations, and layering protocols are determined by your licensed RevelleCare physician based on your clinical assessment. The protocol above represents a typical starting regimen. Individual titration applies.

Physician care & pharmacy,
all-inclusive

The pricing below represents RevelleCare's planned all-inclusive monthly fee at launch. No products or services are currently available. Pricing is estimated and subject to change prior to launch.

Rx Protocol

Est. CAD $70–80 /month

Estimated blended price at launch · Subject to change

  • Physician telemedicine consultation
  • Personalized prescription formulation
  • Compounding pharmacy dispensing
  • Discreet door-to-door delivery
  • Ongoing physician monitoring
  • Prescription renewal management
  • Access to RevelleCare clinical team
Join the Waitlist

Planned launch: Ontario & British Columbia · Fall 2026

Non-Hormonal Option

CAD $65 /month

Non-Hormonal Repair Cream — no Rx required

  • No physician consultation required
  • Vitamin B3, C, E + Bioactive Peptides
  • Compounded to pharmaceutical standards
  • Door-to-door delivery
  • Access to RevelleCare support team
Register Interest

RevelleCare does not bill directly to provincial health plans at this time. Some extended health benefits plans may cover compounded prescription medications — check with your insurer. We provide official receipts for all dispensed prescriptions.

Your Protocol Awaits

Prescription precision,
beautifully designed.

Join the RevelleCare waitlist and be the first to know when we launch in Fall 2026 in Ontario & British Columbia.